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25 Folate Duration of therapy Patients with pernicious anemia require lifelong therapy, while patients with malabsorption require treatment until underlying condition or diet is corrected

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Because of the above evidence for selection of potential revertants and of pGSH1 upregulation upon 5-FOA treatment (implying a generic response), it was concluded that URA3 is not a suitable counter-selectable marker in this system for selection of phenotypically high-GSH producers

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These include subcutaneous immunotherapy (SCIT) and sublingual immunotherapies (SLIT) [122]